Luis's Delgado-Qualtrough's photographic work integrates narrative and sequential still images to create idea-driven content, that answers what cannot be answered and to answer what cannot be questioned. His work has evolved from documentary to a more personal style using humor, and constructed images that reflect his Mexican origins and his European humanist education, with an American quest for the new.
His works have been exhibited worldwide and his prints and artist books have been widely exhibited and are held by many museums, institutions, and private collectors.